Abstract:OBJECTIVE To investigate the application value of enhanced self-care in the patients with diabetic nephropathy (DN) undergoing peritoneal dialysis. METHODS Totally 69 DN patients undergoing peritoneal dialysis were randomly assigned into intervention group (n=35) and control group (n=34). Both groups were given DN routine nursing, and based on this, the intervention group was added enhanced self-care measures. The changes of self-management ability, volume load and glycometabolism indexes were observed between two groups before and 3 months after intervention. RESULTS When compared with before intervention, the scores of exercise, specific and total diets as well as glucose monitoring in intervention group 3 months after intervention went up, while the body weight, systolic pressure, diastolic pressure and dialysate ultrafiltration volume down markedly. All the above-mentioned indexes in intervention group were significantly higher or lower than those in control group (P＜0.05). When compared with before intervention, the levels of fasting blood glucose (FBG), 2-h postprandial glucose (2 hPG) and glycosylated hemoglobin (HbA1c) in both groups decreased obviously 3 months after intervention (P＜0.05), but the decreased range in intervention group was more significant (P＜0.05). CONCLUSION Application of enhanced self-care in DN patients undergoing peritoneal dialysis is conductive to improving self-management ability and volume load condition, control blood glucose.