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中文摘要: 目的 了解上海市浦东新区儿童手足口病和疱疹性咽峡炎临床症状和病原学特征，比较两者的流行病学特征，为有效防控手足口病和疱疹性咽峡炎的发生提供依据。方法 对2016年6月—2017年5月上海市浦东新区手足口病和疱疹性咽峡炎病例进行问卷调查，同时采集病例的咽拭子样本进行肠道病毒检测。结果 疱疹性咽峡炎在一些临床症状上和手足口病表现相似，但发热、咽痛、呕吐及头痛的发生率均高于手足口病病例（P＜0.05）。手足口病与疱疹性咽峡炎的病原学结果不同，手足口病以柯萨奇A6型（CoxA6）、肠道病毒71型（EV71）和柯萨奇A16型（CoxA16）为主，疱疹性咽峡炎以其他肠道病毒和CoxA6为主。结论 疱疹性咽峡炎应该得到重视，并和手足口病一样进行监测管理，有助于进一步提出有针对性的防控措施。
Abstract:OBJECTIVE To understand the clinical symptoms and pathogenic characteristics of hand-foot-mouth disease and herpangina of children in Pudong New Area of Shanghai，and to compare the epidemiological characteristics，provide evidence for effective prevention and control of hand-foot-mouth disease and herpangina. METHODS Questionnaire survey of hand-foot-mouth disease and herpangina was conducted in Pudong New Area of Shanghai from June 2016 to May 2017，and throat swab samples were collected for enterovirus detection. RESULTS Herpangina and hand-foot-mouth disease in some clinical symptoms were very similar, but cases of herpangina fever， sore throat， vomiting and headache were higher than the incidence of hand-foot-mouth disease cases（P＜0.05）. Hand-foot-mouth disease and herpangina etiology results were not the same. The main pathogens of hand-foot-mouth disease were Coxsackie virus A6 （CoxA6）， enterovirus 71 （EV71） and Coxsackie virus A16 （CoxA16）,and the main pathogens of herpangina were other enterovirus and CoxA6. CONCLUSION Herpangina should be stressed, and be monitored and managed like hand-foot-mouth disease to put forward targeted prevention and control measures.
文章编号：3201806018 中图分类号：R52 文献标志码：
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