Abstract:OBJECTIVE To study the clinical difference of maternal pregnancy outcome after uterine leiomyoma rejection. METHODS The uterine myomectomy and tumor pregnancy were enrolled in our hospital from December 2014 to December 2016. In the same period in our hospital delivery of uterine fibroids were divided into two groups: with tumor pregnancy group, to the pregnancy group; access to the two groups of past medical history, recorded in two groups of hospitalized medical records and childbirth complications and fibroids Location, size, quantity relationship. The operation of the patients was recorded and the outcome of maternal pregnancy was compared with the gestational pregnancy group. The effect of the uterine muscle on the maternal pregnancy was analyzed. RESULTS With the tumor pregnancy group the incidence of premature rupture of membranes is lower than the postoperative pregnancy group, with significant difference between the two groups (P＜0.05); the incidence of preterm birth with tumor pregnancy group 0%, pregnancy group is lower than the postoperative 8.7%, with significant difference between the two groups (P＜0.05); the difference was statistically significant postoperative pregnancy group the largest and two groups with tumor pregnancy uterine fibroids diameter (P＜0.05), distribution of the number of myoma in two groups of no statistical significance (P＞0.05), with statistical significance between the two groups, the muscle wall subserosal and submucosal uterine fibroids are the proportion of the difference (P＜0.05). CONCLUSION Although there is a certain negative effect after the removal of uterine myoma, but compared with the tumor pregnancy, postoperative pregnancy will increase the incidence of complications, so for patients with reproductive needs.