Abstract:Objective To investigate the effect of epidural anesthesia on postoperative cognitive function in elderly patients undergoing transurethral resection of prostate. Methods Methods 106 elderly patients who underwent transurethral resection of prostate in our hospital from May 2017 to February 2018 were selected. They were randomly divided into 2 equal groups, the control group received general anesthesia, and the observation group received epidural anesthesia. The anesthetic effects, complications and adverse reactions of the two groups were compared, the mini mental state examination scale (MMSE) was used to evaluate the preoperative and postoperative cognitive function. Results There was no significant difference in onset time and anesthetic effect between the two groups (P＞0.05). The recovery time of anesthesia in the observation group was significantly shorter than that in the control group (P＜0.01). The incidence of bradycardia, urinary retention and hypotension in the observation group was significantly lower than that in the control group (P＜0.05). There was no significant difference in preoperative MMSE score between the 2 groups (P＞0.05). After 7d and 1 months after operation, the MMSE score of the observation group was significantly higher than that of the control group (P＜0.01), and the MMSE score in the control group was lower than that before operation (P＜0.05). Conclusion The effect of epidural anesthesia in the elderly patients with prostatic electrocutting is satisfactory, the incidence of complications and adverse reactions is low, and the cognitive function of the patients is less affected, and it is safe and feasible.