本文已被：浏览 3515次 下载 0次
中文摘要: 目的 分析定西市2014—2018年疑似麻疹病例实验室检测结果和流行病学特征，为制定消除麻疹策略提供依据。方法 采用酶联免疫捕获法（ELISA），对血清标本进行麻疹、风疹 IgM 抗体检测。结果 2014—2018年定西市麻疹网络实验室共检测730份疑似病例的血清标本，检出麻疹IgM抗体阳性186份，阳性率为26.85%，麻疹阳性检出率整体呈逐年下降趋势。麻疹阳性率最高的年龄组为≥20岁组（46.51%），其次为＜8个月组（42.65%）；麻疹发病时间有明显的季节性，集中在3～7月份，各月间麻疹阳性检出率差异有统计学意义。无免疫史和免疫史不详的阳性病例占麻疹阳性病例的比率最高（71.43%）。结论 开展麻疹、风疹监测和检测可及时了解麻疹发病情况和流行病学特征，为制定消除麻疹策略提供科学依据。
中文关键词: 麻疹 麻疹IgM 抗体监测 血清学
Abstract:Objective To analyze the serological test results and epidemiological characteristics of suspected measles cases in Dingxi City from 2014 to 2018, and to provide evidence for the development of measles elimination strategy. Methods Enzyme-linked immunosorbent assay (ELISA) was used to detect measles and rubella IgM antibodies in serum samples of suspected measles cases in Dingxi. Results 730 suspected measles serum samples were detected in Measles Network Laboratory of Dingxi from 2014 to 2018. 186 measles IgM antibodies were positive, the positive rate was 26.85%. The positive rate of measles was decreasing year by year. The age group with the highest positive rate of measles was ≥20 years old (46.51%), followed by <8 months group (42.65%). The onset time of measles was mainly concentrated in March-July, and the difference in the positive rate of measles was statistically significant during months. Positive cases with no history of immunization and unknown immunization account for the highest rate of measles-positive cases (71.43%). Conclusion Measles and rubella surveillance and testing could timely understand the incidence and epidemiological characteristics of measles, and provide a scientific basis for developing measles elimination strategies.
keywords: measles measles IgM antibody monitoring serology
文章编号：3201909022 中图分类号：R511.1 文献标志码：
基金项目:
| Author Name | Affiliation |
引用文本：