Abstract:OBJECTIVE To investigate the role of cognitive behavioral intervention in the care of patients with endometriosis. METHODS 80 patients with endometriosis who were hospitalized from January 2017 to December 2018 were randomly divided into control group and intervention group, with 40 cases in each group. The control group received routine care; the intervention group performed cognitive behavioral intervention on the basis of routine care. The symptomatic self-rating scale (SCL-90) was used to evaluate the psychological state of these two groups before and after intervention. The quality of life was used to evaluate the quality of life before and after intervention. RESULTS The interpersonal relationship and anxiety scores of 80 patients with endometriosis were were significantly higher than the norm, P<0.05; somatization and depression scores were compared with norm, P>0.05. The field of physiology, psychology and social relations was significantly lower than the norm, P<0.05; the environmental field was compared with the norm, P>0.05. The scores of quality factors of the two groups were significantly higher than those before the intervention. The increase of each factor in the intervention group was more obvious than that of the control group, P<0.05. The scores of SCL-90 factors in the two groups were significantly lower than those before the intervention, and the scores of the factors in the intervention group were significantly lower than those in the control group, P<0.05. CONCLUSION Patients with endometriosis had certain psychological problems and their quality of life were affected. Cognitive behavioral intervention could improve their psychological state, improve their quality of life, and reach the norm level, which had high application value.