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中文摘要: 目的 分析天津市2017年疑似预防接种异常反应（Adverse events following immunization，AEFI）的流行病学特征。方法 通过我国免疫规划信息管理系统收集2017年天津市报告的AEFI个案数据，通过天津市免疫规划信息系统收集疫苗接种数据，应用描述性流行病学统计方法进行流行病学分析。结果 天津市2017年共报告2 861例AEFI病例，报告发生率68.61/10万。其中一般反应2 485例（占86.86%），报告发生率59.59/10万；异常反应304例（占10.63%），报告发生率7.29/10万，男、女性别比为1.16∶1，2017年天津市AEFI年龄分布以≤1岁为主(75.25%)，AEFI病例报告时间以第三季度为主；AEFI报告发生率前五位的是13价肺炎疫苗、麻风疫苗、23价肺炎疫苗、百白破IPV和Hib五联疫苗、百白破和Hib四联疫苗。结论 2017年天津市AEFI报告以一般反应为主，严重异常反应报告发生率极低。
中文关键词: 疑似预防接种异常反应 监测
Abstract:OBJECTIVE To analyse the epidemiological characteristics of adverse events following immunization ( AEFI) in Tianjin in 2017. METHODS For descriptive epidemiological analyses, we collected AEFI case data through the National Immunization Program Information Management System, and vaccine doses-administered data from Tianjin Immunization Program Information System. RESULTS In total, 2861 AEFI cases were reported, The reported AEFI incidence was 68.61 per 100,000 doses, 86.86% were common vaccine reactions(2485 cases),10.63% were rare vaccine reactions(304 cases), The reported AEFI incidence were 59.59 per 100,000 doses and 7.29 per 100,000 doses respectively,the male to female ratio was 1.16:1, 75.25% were among children less than 1 years old, Most cases occurred in the third and fourth quarter.The top five AEFI incidence were 13-valent pneumococcal polysaccharide vaccine，Measles and rubella combined attenuated live vaccine，23-valent pneumococcal polysaccharide vaccine, Diphtheria, tetanus and acellular pertussis, inactivated poliovirus and Haemophilus influenzae type b conjugate combined vaccine Diphtheria, tetanus and acellular pertussis and Hhaemophilus influenza type b conjugate combined vaccine. CONCLUSION Most AEFIs were common vaccine reactions in Tianjin in 2017, with an extremely low rate of serious vaccine reactions．
文章编号：3201910022 中图分类号：R1-9 文献标志码：
基金项目:
| 作者 | 单位 |
| 王 伟①，李永成② |
| Author Name | Affiliation |
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