Abstract:OBJECTIVE To observe the clinical effect of eye acupuncture treatment in patients with migraine. METHODS 120 patients diagnosed with migraine in the outpatient clinic were divided into two groups according to the random number table method, with 60 patients in each group. Among them, the control group was treated with conventional scalp acupuncture and body acupuncture treatment，Patient taked a seat while the skin was routinely disinfected, and then acupuncture was performed on the selected acupuncture points by a rapid acupuncture method. The treatment group was treated with eye acupuncture on the basis of the treatment of the control group, and the selected points were acupunctured by lateral acupuncture. After the acupuncture, the needles were left for 45 minutes, once a day, and 21 days was a course of treatment. After 1 course of treatment, the curative effects of the two groups were compared according to the four main aspects: the clinical efficacy judgment standard, headache score (VAS score), TCM syndrome score, and adverse reactions. RESULTS The total effective rate in the treatment group was 95.00%, while the total effective rate in the control group was only 76.67%. There was a statistically significant difference between the two groups (P<0.05). CONCLUSION: Eye acupuncture combined with scalp acupuncture and body acupuncture can effectively alleviate the clinical symptoms of migraine patients, reduce the degree of headache, and have fewer adverse reactions, thereby improving the quality of patients’ life.