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中文摘要: 目的 对高龄备孕妇女生殖道人乳状瘤病毒(HPV)相关知识的认知情况以及感染现状进行调查，并对其HPV感染的相 关危险因素进行探讨。方法 以深圳市福田区妇幼保健院孕前保健门诊2017年7月—2019年7月的1326例高龄备孕妇女为研究 对象，对其 HPV相关知识认知情况和 HPV感染的相关危险因素进行调查，并取宫颈分泌物进行 21种 HPV基因型检测。结 果 1326例研究对象 HPV相关知识知晓总分为 20分，平均(11.23?2.09)分，低于平均分数。其中 HPV感染者的平均得分为 （9.70?1.52）分，未感染者的平均得分为（13.69?1.75）分，两组比较，差异有统计学意义（P＜0.05）；检测出HPV感染率为9.28%， 感染亚型主要为16，52，11，58，68；长期使用避孕套、口服避孕药、生殖道感染和丈夫阴茎包皮过长、吸烟等都与HPV感染 关系较大。结论 高龄备孕妇女HPV相关知识认知度低，长期使用避孕套口服避孕药、生殖道感染和丈夫阴茎包皮过长、吸烟 等都与HPV感染关系较大。宫颈癌的发展过程与HPV的持续性感染，以及各亚型的相互作用密切相关，且高龄女性具有更高的 宫颈癌患病风险。应开展有针对性的健康宣教活动，提高育龄妇女HPV相关知识的认知度，从而降低HPV感染率。
Abstract:Objective To understand the status of reproductive human papillomavirus (HPV) infection in elderly pregnant women and to explore the risk factors associated with HPV infection in this population. Method Taking 1326 elderly pregnant women in the pre-pregnancy health clinic of Shenzhen Futian District Maternal and Child Health Hospital from July 2017 to July 2019 as the research object, the HPV related knowledge cognition and the related risk factors of HPV infection were investigated, and 21 HPV genotypes were detected by cervical secretion. ResultsThe cognition of HPV related knowledge in 1326 subjects was moderate; the HPV infection rate was 9.28%, with major subtypes of infection 16,52,11,58,68; long-term condom use of the oral contraceptive pill, genital tract infections and excessive prepuce of the husband's penis, smoking and so on are all associated with HPV infections. Conclusion Chronic use of condoms oral contraceptive pills, genital tract infection and husband's penis prepuce too long, smoking and so on are related to HPV infection.
文章编号：3202003230 中图分类号：R714 文献标志码：
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| 作者 | 单位 |
| 林叙君①，彭文湃①，罗佳燕① |
| Author Name | Affiliation |
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