Abstract:OBJECTIVE To explore the influencing factors of anxiety and depression of family members of patients with advanced cancer and the effect evaluation of intervention model of multidisciplinary team participating in family meeting. METHODS Through a questionnaire survey of 72 family members (main caregivers) of advanced cancer patients in a community health service center in Pudong New Area of Shanghai from January to March 2019, to understand their anxiety and depression, and analyze the influencing factors.On the basis of the baseline investigation, 72 family members of patients were divided into intervention group and control group according to the method of digital random table, and they were given routine comprehensive services. On this basis, the intervention group organized a multi-disciplinary family meeting, and the intervention effect was evaluated with anxiety scale (SAS) and Depression Scale (SDS). The intervention time was 6 months. RESULTS Before the intervention, the SAS and SDS scores of the family members of the patients were significantly higher than those of the domestic norm(P<0.001), and the SAS and SDS scores between the intervention group and the control group were in the baseline balance(P>0.05).The results of univariate analysis showed that there were significant differences in SAS and SDS scores among different genders, education levels and families with or without fixed occupation(P<0.05). After 6 months of intervention, compared with the control group, the SAS and SDS scores of family members in the intervention group were lower than those in the control group (P<0.001). CONCLUSION Family members of patients with advanced cancer have obvious anxiety and depression, which are related to their gender, education level and occupational status; family meeting intervention with multi-disciplinary team participation can effectively improve the anxiety and depression of family members of patients with advanced cancer.