Abstract:OBJECTIVE To explore the effect of body mass index (BMI) on cardiovascular disease secondary to polycystic ovary syndrome (PCOS), to provide direction for clinical intervention. METHODS 120 outpatients from rehabilitation medical center of The First Affiliated Hospital of Nanjing Medical University were selected. According to BMI, they were divided into three groups, 30 in each group. Another 30 healthy subjects were selected as the control group to study the center rate, blood pressure change, peak ex⁃ ercise ability and BMI relevance. RESULTS There was a significant correlation between heart rate drop and BMI at 1, 3 and 5 min⁃ utes after exercise (P＜0.05). At the end of the treadmill exercise test, 1 min correlation analysis showed that the systolic blood pres⁃ sure recovery ratio was significantly correlated with BMI (P＜0.05). The recovery ratio of systolic blood pressure in PCOS group was higher than 0.8 three minutes after the end of treadmill exercise test. In the correlation analysis, MaxMETs was significantly correlat⁃ ed with BMI (P＜0.05). CONCLUSION Obesity played an important role in the occurrence and development of cardiovascular compli⁃ cations in patients with PCOS, which needed more clinical attention.