Abstract:Objective To explore the clinical value of psychological assessment in the diagnosis and treatment of breast cancer patients and the changes of serum IL-1β and TNF-ɑ levels before and after chemotherapy and its clinical significance.Methods: A total of 140 patients with breast cancer collected were divided into chemotherapy group (n = 70) and control group (n = 70) (group B). Both groups were treated with conventional chemotherapy , Group B patients in the course of treatment to assess the psychological level, and accordingly adjust the treatment program and give appropriate psychological intervention, and test the serum levels of IL-1β, TNF-ɑ in both groups and compare the results of the test Changes in the relationship between the clinical significance and the effect of treatment.Results: After treatment, the levels of IL-1β and TNF-ɑ in the two groups were significantly lower than those before treatment (P <0.05), and the difference between group B and group A (P <0.05) Psychological depression has improved, B group than the A group of psychological score lower. Conclusion: (1) In the course of clinical treatment, psychological evaluation combined with chemotherapy in the treatment of breast cancer is better than chemotherapy alone. Should be on the psychological evaluation of breast cancer patients to the clinical treatment to the timely treatment of the program will significantly improve the quality of life and clinical symptoms, improve clinical efficacy; (2) in the diagnosis and treatment process, the psychological aspects of patients Assessment will better guide the clinical treatment, the prognosis of patients with a clearer understanding, more conducive to improving the patient's long-term prognosis and quality of life, but also for clinical workers to provide a new treatment; (3) clinical work Can be through the abnormal changes in IL-1β, TNF-ɑ to predict the treatment of breast cancer patients, the severity of the disease and prognosis.