Abstract:OBJECTIVES To study the effect of humanized nursing intervention on improving the tolerance of patients with breast cancer after Radiotherapy, chemotherapy and the impact on prognosis of quality of life. METHODS 80 cases of breast cancer patients from January 2016 to June 2017 in our hospital were selected as the object of study. All patients were divided into two groups according to the random number table method, each group of 40 cases. The patients in the control group were given routine care, and the patients in the observation group were treated with routine nursing care on the basis of routine nursing. The self-Rating anxiety scale, the Self-Rating Depression Scale score and the Prognostic Quality of Life (SD) score were compared between the two groups before and after the nursing intervention. RESULTS The tolerance of the observation group was 97.50%, which was higher than which in the control group [80.00%(32/40)], the difference was statistically significant (P﹤0.05).There was no significant difference in quality of life between the two groups before treatment (P﹥0.05).After the intervention, the quality of life of both groups improved, and the observation group was higher than the control group (P﹤0.05);There was no significant difference in the scores of negative emotion (SDS, SAS) between the two groups before treatment (P﹥0.05).After 6 months of treatment, the negative mood (SDS, SAS score) decreased, and the observation group was lower than the control group (P﹤0.05).CONCLUSIONS For breast cancer patients, radiotherapy to give human care intervention can better improve patient treatment tolerance and quality of life, all patient-centered, improve patient satisfaction, enhance the confidence of treatment, improve the nurse room Of the relationship between the clinical application worthy of further promotion.