Abstract:OBJECTIVE To analyse of four coagulation tests and lipid levels in postmenpausal women with type 2 diabetes mellitus (T2DM),and the relationship of these parameters with angiopathy.METHODS The levels of prothrombin time(PT),partial thromboplastin time (APTT),thrombin time(TT),fibrinogen(FIB) and the total cholesterol（TC）triglycerides（TG）low density lipoprotein choliesterols（LDL-C）and high density lipoprotein cholesterols（HDL-C）were determined in postmenpausal women with type 2 diabetes mellitus (n= 205)and controls (n= 105). RESULTS　Compared with those of control group,the levels of PT,APTT were significantly shorter in diabetes mellitus,the level of fibrinogen (FIB) increased.Furthermore,in diabetes patients,those with angiopathy showed shorter the levels of PT,APTT,TT and higher the level of FIB.Meatime, Compared with those of control group,the levels of TG,TC and LDL-C were significantly higher in diabetes mellitus, Furthermore,in diabetes patients,those with oangiopathy showed shorter the levels of TG, TG and higher the rate of combined hyperlipidemia. CONCLUSION　Four coagulation tests and lipid levels monitoring could play an important role in diseases analysis, angiopathy diagnosis and prevention of diabetic complications．we ought to examine coagulation parameters and the plasma lipids in those patients as early as possible.