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中国初级卫生保健:2018,32(6):14-15
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H型高血压在上海世博家园社区的发病特点及干预*
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中文摘要: 目的 分析H型高血压在上海世博家园社区的发病特点及小剂量叶酸在H型高血压中的治疗价值。方法 对2015年3月—2017年3月上海市迎博社区卫生服务中心门诊的成人高血压患者进行HCY检测,HCY≥10 umol/L定义为升高,观察其性别、年龄和生活习惯等。筛选出160例高血压患者,采用随机数字表法将患者分为普通降压组和联合叶酸组,每组各80例,普通降压组患者采取依那普利治疗,10 mg/d,口服,联合叶酸组在普通降压组的基础上给予叶酸治疗,0.8 mg/d,口服,同时选取在卫生服务中心进行治疗的未合并高同型半胱氨酸血症的非H型高血压患者160例,观察两组患者的临床特点、知晓率、治疗率和控制率比较两组治疗效果及预后。结果 非H型高血压患者男性发病率、年龄、收缩压、舒张压、肌酐和尿酸均显著低于H型高血压患者;控制率、知晓率和治疗率显著高于H型高血压患者。治疗后联合叶酸组与普通降压组比较,收缩压、舒张压和血中同型半胱氨酸水平均显著低于普通降压组(P<0.O5)。结论 H型高血压患者高发于中老年男性患者,对于心脑血管血管以及肾脏均有严重影响,小剂量叶酸可以有效治疗H型高血压,改善预后。
Abstract:OBJECTIVE To analyze the characteristics of h-type hypertension in community health service center and the therapeutic value of low dose folic acid in h-type hypertension. METHODS In March 2015 to March 2017 community health service center of Shanghai ying bo outpatient HCY tests of adult patients with high blood pressure, higher HCY 10 umol/L or defined as, observe the gender, age, living habits, etc.Selected 160 cases of patients with high blood pressure, using the random number table method divided the patients into drug groups and the combined folic acid groups, each group of 80 cases patients with drug groups treated with enalaprilat, 10 mg/d, oral, combined folic acid group on the basis of drug groups given folic acid treatment, 0.8 mg/d, oral, and in the health service center for treatment of unincorporated high homocysteine levels, 160 cases of patients with essential hypertension (eh) and to observe the clinical characteristics of two groups of patients, awareness, treatment and control rates compare two groups of therapeutic effect and prognosis.RESULTS The incidence, age, systolic blood pressure, diastolic blood pressure, creatinine and uric acid were significantly lower in patients with primary hypertension compared with h-type hypertension.The control rate, awareness rate and treatment rate were significantly higher than those with h-type hypertension.After treatment, the combined folic acid group and the antihypertensive group were compared, systolic blood pressure, diastolic blood pressure, and homocysteine levels in blood were significantly lower than that in the blood pressure group(P<0.O5).CONCLUSION H high incidence of hypertension patients in middle-aged and old male patients, for the blood vessel of brain blood vessels and kidneys were seriously affected, the small dose of folic acid can effectively treat H high blood pressure, improve the prognosis.
文章编号:3201806005     中图分类号:R197    文献标志码:
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