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中文摘要: 目的 分析吴江区2008—2010年恶性肿瘤患者生存状况，为吴江区肿瘤综合防治提供科学依据。方法 收集、整理吴江区2008—2010年登记报告肿瘤新发病例6 418例的病历资料，随访截止至2015年12月31日。采用寿命表法计算观察生存率，采用Kaplan-Meier法计算平均生存期和中位生存期，采用Log-rank 检验比较不同性别、年龄组患者的生存情况，利用Cox回归模型对肿瘤生存率进行多因素分析。结果 吴江区2008—2010年5年观察生存率前5位肿瘤分别为乳腺癌(62.70%）、卵巢癌(58.36%）、子宫颈癌(58.24%）、甲状腺癌(53.51%）和子宫体癌(42.24%)，后5位分别为胰腺癌(4.97%）、肝癌(7.50%）、骨癌(10.09%）、食管癌(10.25%)和肺癌(14.88%)。男性、女性恶性肿瘤患者5年观察生存率分别为19.50%和33.20%，＜55岁患者5年观察生存率为43.54%，55～65岁为31.83%，65～75岁为19.67%，≥75岁为9.99%。女性肿瘤患者死亡风险是男性的0.79倍，≥75岁组患者死亡风险是＜55岁组患者的2.61倍；女性肺癌死亡风险是男性的0.79倍，女性肝癌死亡风险是男性的1.24倍。结论 在吴江区登记的主要恶性肿瘤中，乳腺癌、结直肠肛门癌生存状况较好，胰腺癌、肝癌、肺癌和胃癌生存状况较差；女性恶性肿瘤患者总体生存状况好于男性；随着年龄的增加，恶性肿瘤生存率不断下降；男性肺癌死亡风险高于女性，女性肝癌死亡风险高于男性。
Abstract:OBJECTIVE Analyze the survival status of malignant tumor patients during 2008-2010 in Wujiang district, to provide scientific basis for comprehensive prevention and control of tumor. METHODS A total of 6418 new cases of neoplastic cases in the 2008-2010 year registration report of Wujiang district were collected and arranged, and the follow-up was up to December 31, 2015. The survival rate was calculated by the life table method, and the average life and median survival time were calculated by Kaplan - Meier method. Log-rank test to compare the survival of different gender, age groups, Cox regression model for tumor survival by multivariate analysis. RESULTS Five year survival rates in the top five cancers were breast cancer (62.70%), ovarian cancer (58.36%), cervical cancer (58.24%), thyroid carcinoma(53.51%), uterine body cancer (42.24%).Five year survival rates in the lowest fives were respectively pancreatic cancer(4.97%), liver cancer(7.50%), bone tumors(10.09%), esophageal cancer(10.25%), lung cancer (14.88%). Five year observed survival rates in male and female were 19.50% , 33.20% respectively. Five year observed survival rates in age group ＜55 , 55～65, 65～75, ≥75 years were 43.54%, 31.83%, 19.67%, 9.99%. Female patients with the risk of death was 0.79 times of the male, aged ≥75 years old group had a risk of death was 2.61 times ＜55 years old group. The risk of death in women's lung cancer is 0.79 times as high as that of men, and the risk ofdeath for women's liver cancer is 1.24 times more than that of men. CONCLUSION It is shown from the results above that the survival rates of breast cancer and colorectal cancer were relatively better in Wujiang, but the survival rate of pancreatic cancer, liver cancer, lung cancer and gastric cancer were significantly lower. The overall survival of women with malignant tumor is better than that of men. With the increase of age, the survival rate of malignant tumor is decreasing. The risk of death in male lung cancer is higher than that of women, and the risk of death of female liver cancer is higher than that of male.
keywords: cancer survival rates Epidemiology Wujiang
文章编号：3201809020 中图分类号：R73-31 文献标志码：
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