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中文摘要: 目的 观察良附丸加减联合化疗对胃癌术后患者生活质量的影响。方法 选取2016年6月—2017年12月在大连市金州新区中医医院住院的胃癌术后患者40例,采用随机数字表随机分为对照组和观察组,每组各20例。对照组采用单纯化疗的治疗方案进行治疗。观察组在对照组治疗的基础上加用良附丸加减治疗,治疗30天,随访3个月。于治疗30天后和随访第3个月末观察两组的治疗效果、患者的生活质量和不良反应发生率。结果 治疗30天后,观察组临床总有效率、生活质量评分和不良反应发生率均优于对照组(P<0.05或P<0.01);随访3个月末时,观察组临床总有效率和生活质量评分优于对照组(P<0.05或P<0.01);随访期间两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论 良附丸加减联合化疗对胃癌术后患者的治疗效果更优,中药可能通过其增效减毒作用提高患者的生活质量,降低化疗初期的不良反应发生率。
Abstract:OBJECTIVE To observe the effects of Liangfu Pills combined with chemotherapy on the quality of life of postoperative gastric cancer patients, and to analyze the therapeutic mechanism of Liangfu Pills.METHODS 40 patients with postoperative gastric cancer who were hospitalized in Jinzhou New District Chinese Medicine Hospital from June 2016 to December 2016 were randomly selected and divided into two groups according to the random number table of the patient's hospitalization number. 20 cases. The control group was treated with chemotherapy alone. The observation group was treated with addition and subtraction of Liangfu Pill on the basis of treatment in the control group. Treatment for 30 days was followed up for 3 months. After 30 days of treatment and at the end of the third month of follow-up, the treatment effects, quality of life, and incidence of adverse reactions were observed in both groups.RESULTS After 30 days of treatment, the results of clinical total effective rate, quality of life score, incidence of adverse reactions in the observation group were better than those in the control group (P<0.05 or P<0.01). At the end of the 3-month follow-up, the clinical total effective rate and quality of life scores in the observation group were better than those in the control group (P<0.05 or P<0.01). The incidence of adverse reactions during follow-up was not statistically significant between the two groups (P>0.05). CONCLUSION Liangfu Pills combined with chemotherapy combined with chemotherapy has a better therapeutic effect on postoperative patients with gastric cancer. Chinese medicine may improve the quality of life of patients through its synergistic and attenuating effects, and reduce the incidence of adverse reactions at the early stage of chemotherapy.
keywords: Gastric cancer Postoperative gastric cancer Liangfu pill Chemotherapy Quality of life Therapeutic effect
文章编号:3201809028 中图分类号:R179 文献标志码:
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