Abstract:OBJECTIVE To compare the clinical efficacy of methotrexate combined with hysteroscopic electrocision and curettage in the treatment of type I scar pregnancy. METHODS 52 cases of cicatricial pregnancy diagnosed by color Doppler ultrasound were divided into 2 groups according to the operation mode, one group was the observation group, the methotrexate combined with hysteroscopy, and the other group was treated with methotrexate combined hysteroscopy. The time of the decrease of serum beta -HCG to the normal level, the time of operation, the time of hospitalization, the amount of bleeding in the operation，the recovery of normal menstruation and the postoperative complications and complications were observed and compared between the two groups. RESULTS two groups of patients successfully completed the operation, there was no case of hysterectomy due to massive bleeding. The level of serum beta -HCG in the observation group was lower than that of the control group (P﹤0.05), and the amount of bleeding in the observation group was significantly lower than that of the control group (P﹤0.05). The difference was statistically significant. The incidence of bad and complications in the observation group was lower than that in the control group (P ﹤0.05), and the difference was statistically significant. CONCLUSION methotrexate combined with hysteroscopy in the treatment of cicatricial pregnancy has high success rate, rapid recovery, less bleeding and less adverse reactions in the operation, which is beneficial to the retention of uterus and reproductive function.