Abstract:OBJECTIVE To investigate the effect of psychological intervention assisting of basic treatment on the clinical efficacy and negative emotion of patients with moderate/severe periodontitis and anxiety. METHODS The clinical data of 92 patients with moderate/severe periodontitis and anxiety in our hospital from March 2015 to March 2016 were retrospectively analyzed. According to the different nursing methods in the results, the patients were divided into control group and study group with 46 cases in each group. The patients in the two groups were treated with periodontal treatment. The cases in the control group were given routine nursing intervention, and the cases in the study group were given with psychological intervention. the intervention of the two groups were carried out for 4 weeks. The periodontal index, negative emotion and satisfaction with nursing care after intervention in two groups were compared. RESULTS (1)after nursing intervention, the periodontal index were significantly lower than those before nursing intervention in two groups, and the periodontal index in the study group were significantly lower than that in the control group (P<0.05); (2) after nursing intervention, the SAS and SDA of the two groups were significantly decreased compared with before intervention, and the decreased degree of the study group were significantly larger than that of the control group (P<0.05); (3) the total nursing satisfaction of the study group was significantly higher than that in the control group (95.65% vs 76.09%) (P<0.05). CONCLUSION Psychological intervention assisting of basic periodontal treatment can effectively improve periodontal index in patients with moderate or severe periodontitis accompanied by anxiety, reduce the degree of anxiety and depression, which are more easily accepted by patients.