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中文摘要: 目的 探讨沙参麦冬汤合五味消毒饮养阴清热、解毒散结对中晚期肺癌阴虚毒热证老年化疗患者增效减毒的效果。 方法 将70例中晚期肺癌老年患者随机分为对照组和观察组，每组各35例。对照组患者采取常规放化疗方案，观察组在对照组基础上采取沙参麦冬汤合五味消毒饮治疗，1剂/d，2次/d。连续治疗6周后，比较两组患者的近期疗效、毒副反应和生活质量改善情况。结果 治疗6周后，观察组患者的近期总有效率为80%，显著高于对照组的54.29%(P＜0.05)。化疗期间，观察组患者白细胞减少、恶心呕吐和肝功能损伤的发生率显著低于对照组(P＜0.05)；治疗6周后，观察组患者的生活质量评分高于对照组，差异有统计学意义(P＜0.01)。结论 养阴清热、解毒散结的沙参麦冬汤合五味消毒饮能够提高中晚期老年肺癌患者的近期疗效，减轻毒副反应，改善患者的生活质量。
Abstract:OBJECTIVE To investigate the effect-enhancing and toxicity-reducing of Yangyin Qingrei and Liangxue Sandu of Shashen Maidong decoction and Wuwei Xiaodu decoction on advanced lung cancer with syndrome of yin deficiency and toxic-heat. METHOD Seventy advanced lung cancer cases were randomly divided into the control and the observation group (35 cases in each group).The control group received the routine chemotherapy regimens.On basis of the control group,the treatment group orally received Shashen Maidong decoction and Wuwei Xiaodu decoction(1 dose/d and bid).After 6 weeks’ treatment,the recent efficacy,the adverse reactions,and life quality were compared in two groups. RESULTS After 6 weeks’ treatment,the recent efficacy rate (80%) was obviously higher than the control group 54.29%(P＜0.05).During chemotherapy,the incidence rate of leukopenia,nausea and vomiting,and liver damage in the observation group was significantly lower than those in the control group(P＜0.05). After 6 weeks’ treatment, the life quality of the observation group was higher than the control group, with statistically significant differences(P＜0.01).CONCLUSION Shashen Maidong decoction and Wuwei Xiaodu decoction with the effect of Yangyin Qingrei and Liangxue Sandu can increase the recent efficacy,reduce side effects,and improve patients' quality of life
keywords: shashen maidong decoction wuwei xiaodu decoction lung cancer syndrome of yin deficiency and toxic-heat
文章编号：3201903025 中图分类号：R681 文献标志码：
基金项目:
| 作者 | 单位 |
| 王 凯① |
| Author Name | Affiliation |
引用文本：