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中文摘要: 目的 研究亚胺培南对老年性肺炎患者细胞免疫功能及C反应蛋白（C-reactive protein，CRP）、降钙素原（Procalcitonin，PCT）的影响。方法 选取上海市嘉定区迎园医院2015年6月—2018年6月接诊的96例老年性肺炎患者进行研究。根据患者住院ID号，将其随机均分为对照组和观察组。对照组采取常规治疗，观察组采取亚胺培南治疗。比较分析两组患者的治疗10 d后的效果。结果 观察组治疗10 d后总有效率（95.83%）明显高于对照组（79.16%，P＜0.05)。治疗10 d后，两组患者的CD3+、CD4+和CD4+/CD8+均明显升高，但观察组CD3+、CD4+和CD4+/CD8+均明显高于对照组(P＜0.05)。观察组CRP、PCT水平均明显低于对照组(P＜0.05)。结论 亚胺培南治疗老年性肺炎的疗效显著，能够改善患者的细胞免疫功能，值得应用及推广。
Abstract:OBJECTIVE To study the effects of meropenem on cellular immune function and C-reactive protein (CRP) and procalcitonin (PCT) in elderly patients with pneumonia. METHODS 96 cases elderly patients with pneumonia in Yingyuan Hospital, Jiading District, Shanghai from June 2015 to June 2018 were selected for the study. According to the ID number of the patients, they were randomly divided into control group and observation group. The control group received routine treatment, while the observation group received meropenem treatment. The effects of 10 days after treatment were compared and analyzed between these two groups. RESULTS The total effective rate of the observation group (95.83%) was significantly higher than the control group (79.16%, P＜0.05). After 10 days of treatment, the levels of CD3+,CD4+,CD4+/CD8+ in the two groups were significantly increased, but the levels of CD3+,CD4+,CD4+/CD8+ in the observation group were significantly higher than the control group(P<0.05). The levels of CRP and PCT in the observation group were significantly lower than the control group, the difference between the two groups were statistically significant(P＜0.05). CONCLUSION Meropenem was effective in the treatment of senile pneumonia, and it could improve the cellular immune function of patients, which was worthy of application and promotion.
文章编号：3201906031 中图分类号：R563.1 文献标志码：
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| 作者 | 单位 |
| 陈金亚①，何红梅②，李 莉② |
| Author Name | Affiliation |
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