Abstract:Objective To explore the effect of VSD technique on infection after fracture surgery. Methods 60 cases of patients with infection after fracture surgery were grouped according to different treatment methods. Traditional treatment group (30 cases) was treated with traditional continuous perfusion therapy. VSD treatment group (30 cases) was treated with VSD technique. The clinical efficacy, infection control time, McGill pain score and hospital stay were compared. Elisa method was used to detect the levels of IL-6, IL-8 and hs-CRP in the serum of patients before and after treatment, and the PCT level in serum was detected by electrochemiluminescence. Results There was no statistically significant difference between these two groups about clinical effect. The time of infection control of VSD treatment group was significantly shorter than traditional treatment group, and the difference was statistically significant (P < 0.01). The pain score of McGill in the VSD treatment group was significantly lower than the traditional treatment group, and the difference was statistically significant (P ＜0.01). The levels of IL-6, IL-8, hs-CRP and PCT were significantly lower in each group than in the previous treatment, and the difference was statistically significant(P＜0.01). The levels of IL-6, IL-8, hs-CRP and PCT were significantly lower than the traditional group after treatment of VSD treatment group, and the difference was statistically significant (P＜ 0.01). Conclusion Compared with the traditional continuous flooding method, the VSD was easy to operate, which significantly reduced the time of infection control, hospital stay time and alleviates. the pain of the patient, and can effectively control the development of infection after fracture.