Abstract:Objective To evaluate the effect of ultrasound-guided paravertebral block on postoperative analgesia in patients undergoing percutaneous nephrolithotomy. Methods A total of 60 patients undergoing percutaneous nephrolithotomy were selected from January 2016 to June 2018, ASA grade II～III. The patients were randomly divided into P group (n=30) and C group (n=40). The mean arterial pressure (MAP) and heart rate (HR) were recorded at the time of anesthesia induction (T0), the beginning of operation (T1), the time of Channel setup completion (T2) and the end of operation (T3). VAS score was assessed immediately after PACU, at 2h, 4h, 12h after operation. The incidence of complications such as postoperative nausea and vomiting (PONV) and dizziness were recorded. Results The levels of MAP and HR in group C were significantly higher than those in group P at T1, T2and T3. The VAS score in group P were significantly lower than those in group C. The incidence of PONV in group P were significantly lower than those in group C. There was no statistically significant difference in the incidence of pruritus ,dizziness and drowsiness between these two groups(P>0.05). Conclusion Ultrasound-guided paravertebral block was helpful to maintain the stability of hemodynamics in patients undergoing percutaneous nephrolithotomy, and could provide good postoperative analgesic effect.