Abstract:OBJECTIVE To understand the relationship between perceived organizational support, psychological contract breach and turnover intention among general practitioners, aiming to provide insights for the improvement of incentives for general practitioners. METHODS During the period from June to December 2016, two-wave survey was conducted among the general practitioners of the Community Health Centers in Pudong New District, Shanghai. The main contents of the first survey included demographic information, perceived organizational support, and psychological contract breach. The second survey measured the turnover intention. SPSS 24.0 and AMOS 24.0 were applied. RESULTS Among 1 145 general practitioners, the mean of perceived organizational support scored 4.59±0.85, psychological contract breach scored 3.13±0.53, and turnover intention scored 2.26±0.95. Perceived organizational support had a negative effect on turnover intention, and psychological contract breach had a positive effect on turnover intention, and psychological contract breach had negative effect on perceived organizational support, and perceived organizational support had a partial mediating role on the relationship between psychological contract breach and turnover intention. CONCLUSION The incentive policy for general practitioners in Pudong New District of Shanghai needed to be further improved from the aspects of strengthening policy interpretation, guaranteeing implementation, and emphasizing on career development.