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中文摘要: 目的：通过分析上海市金山区同一批体检人群两次健康体检结果，探讨非酒精性脂肪性肝病（NAFLD）的患病 率、转归情况以及NAFLD与代谢综合征各组分指标间的关系。方法：对2017年、2019年连续参加上海市金山区居民体检的
3 769 例居民进行肝脏超声和人群体格、血生化检查。结果：2017 年、2019 年该人群 NAFLD 检出率分别为 28.10％和
18.17％。相对于两次均阴性组，两次均阳性组检出代谢综合征风险最高。随着 MetS 异常成分检出数量增加，研究对象患
NAFLD的风险增加。多因素分析，超重或肥胖对 NAFLD影响最大，其次为血脂紊乱、糖尿病和高血压，年龄是保护因素。
结论：该地区 NAFLD检出率与年龄相关，女性检出率高于男性。NAFLD与 MetS各组分关系密切，体质指数对 NAFLD影响
最大，NAFLD防治应重点关注肥胖人群。
中文关键词: 代谢综合征 非酒精性脂肪肝 居民体检
Abstract:OBJECTIVE By analyzing the results of two physical examination of the same group of people in Jinshan District of
Shanghai，it discussed the prevalence and prognosis of nonalcoholic fatty liver disease（NAFLD），as well as the relationship be⁃
tween NAFLD and each component index of metabolic syndrome. METHODS 3 769 residents who participated in the physical exami⁃
nation of Jinshan District residents in 2017 and 2019 were examined by liver ultrasound，physical examination and blood biochemi⁃
cal examination. RESULTS The detection rates of NAFLD in 2017 and 2019 were 28.10% and 18.17%，respectively. Compared
with negative group，NAFLD positive group had the highest risk of METS detection. As the number of METS abnormal components
increased，the risk of NAFLD increased. In the multi-factor analysis of NAFLD，overweight or obesity had the greatest impact on
NAFLD. Dyslipidemia， diabetes and hypertension， and age were the protective factors. CONCLUSIONS The detection rate of
NAFLD in the area was related to age，and the detection rate of female was higher than that of male. NAFLD was closely related to
METS. BMI had the greatest impact on NAFLD，so the prevention and treatment of NAFLD should focus on obese people.
文章编号：3202106027 中图分类号：R575.5 文献标志码：
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