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中文摘要: 摘 要：目的：分析2023年上海市松江区女性乳腺癌及生殖系统主要恶性肿瘤的发病情况及2011—2023年发病的变化 趋势，为制定和优化防控措施提供依据。方法：利用上海市松江区肿瘤登记数据，计算女性乳腺癌、宫颈癌、子宫体癌及 卵巢癌发病率与标化发病率。标化发病率以2000年第五次全国人口普查的标准人口年龄构成计算，采用Joinpoint 4.9.1.0软 件计算发病率的变化趋势。结果：2023年上海市松江区女性乳腺癌、宫颈癌、子宫体癌及卵巢癌粗发病率分别为83.38/10 万、13.85/10万、11.95/10万、12.22/10万，其标化发病率分别为47.01/10万、8.72/10万、6.89/10万、5.57/10万。2011一 2023年上海市松江区女性乳腺癌粗发病率及标化发病率均呈明显上升趋势(粗APC=3.99%, 标 化APC=2.56%,P<0.01),
且50~79岁发病率显著上升；2011 — 2019年宫颈癌粗发病率显著上升( APC=4.93%,P<0.05),35~39 岁发病率显著下 降 ( APC=-9.71%,P<0.01); 子宫体癌整体粗发病率与标化发病率均无显著变化趋势( P>0.05),65~69 岁发病率显著 下 降( APC=-6.19%,P<0.05); 标化发病率显著下降( APC=-3.78%,P<0.01), 卵巢癌70~74岁发病率显著下降 ( APC=-8.67%,P<0.01) 。 结论：上海市松江区年轻女性宫颈癌发病率降低，但仍存在乳腺癌发病率持续上升、不同癌种 负担显著等问题。
Abstract:Abstract: OBJECTIVE To analyze the incidence of female breast cancer and major reproductive system malignancies in Songjiang District of Shanghai in 2023,as well as the incidence trends from 2011 to 2023,and to provide evidence for the development and optimization of prevention and control strategies. METHODS Using cancer registry data from Songjiang District of Shanghai,the crude incidence rates and age standardized incidence rates(ASIR)of female breast cancer,cervical cancer,uterine corpus cancer,and ovarian cancer were calculated.The ASIR was standardized using the age composition of the standard population from the Fifth National Population Census in 2000.Joinpoint 4.9.1.0software was used to analyze incidence trends.RESULTS In 2023,the crude incidence rates of female breast cancer, cervical cancer,uterine corpus cancer,and ovarian cancer in Songjiang District of Shanghai,were 83.38/100,000,13.85/100,000, 11.95/100,000,and 12.22/100,000,respectively,with coresponding ASIR of 47.01/100,000,8.72/100,000,6.89/100,000,and 5.57/100,000.From 2011 to 2023,both the crude and age standardized incidence rates of female breast cancer showed significant upward trends(APC=3.99,APC=2.56,P<0.01),with a marked increase in the 50-79 age group.The crude incidence rate of cervical cancer increased significantly from 2011 to 2019(APC=4.93,P<0.05),while a significant decrease was observed in the 35-39 age group (APC=9.71,P<0.01).For uterine corpus cancer,neither the overall crude nor agestandardized incidence rates showed significant trends(P>0.05),though a significant decrease was found in the 65-69 age group(APC=-6.19,P<0.05).For ovarian cancer,the crude incidence rate showed no significant change(APC=-2.27,P=0.145),but the agestandardized incidence rate decreased significantly (APC=3.78,P<0.01),with a marked decrease in the 70-74 age group(APC=-8.67,P<0.01).CONCLUSION The incidence of cervical cancer among young women in Songjiang District of Shanghai has decreased.However,challenges remain,including the continuously increasing incidence of breast cancer and the varying age specific burden across different cancer types.
keywords: Keywords:breast cancer cervical cancer uterine corpus cancer ovarian cancer incidence trends
文章编号：3202410010 中图分类号：R73 文献标志码：
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