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中文摘要: 摘 要:目的:分析2011—2023年定西市风疹流行病学特征,并对风疹确诊病例的病毒株基因型进行监测。方法:采
用描述性流行病学方法,对2011—2023年风疹发病率、时空分布、人群特征及免疫史进行分析。结果:2011—2023年,定
西市共报告风疹病例1155例,年均发病率为2.95/10万。2011—2018年发病率维持在很低水平,2019年风疹发病率达到历史
最高水平。风疹病例全年各月均有报告,但有明显的季节性,主要集中在3—6月份。定西市各县区均有风疹病例报告,发
病率最高的是漳县;发病年龄以12~23岁为主,占病例总数的94.64%。发病人群主要以学生为主,占病例总数的97.40%, 无含风疹成分疫苗免疫史和免疫史不详的病例占92.64%。定西市风疹病毒株的基因型为1E和2B基因型。结论:定西市风疹
流行呈现明显年龄聚集性和免疫空白,需加强青少年群体疫苗接种和学校疫情防控。
Abstract:Abstract:OBJECTIVEToanalyzetheepidemiologicalcharacteristicsofrubellacasesinDingxifrom 2011to2023,andto
monitorthegenotypeofconfirmedrubellacases.METHODSDescriptiveepidemiologicalmethodwasusedtoanalyzetheincidence
rate,epidemiologicalcharacteristicsandimmunehistoryofrubellacasesinDingxi.RESULTSAtotalof1155rubellacaseswere
reportedinDingxifrom2011to2003,withanaverageannualincidencerateof2.95/105
.Theincidencerateofrubellaremainedata
verylowlevelfrom2011to2018,andtheincidencerateofrubellareachedthehighestlevelinhistoryin2019.Rubellacaseshad
beenreportedineverymonthoftheyear,buttherewasaclearseasonalpattern,mainlyconcentratedfrom MarchtoJune.All
countiesanddistrictsinDingxihadreportedcasesofrubella,andZhangxianCountyhadthehighestincidencerate.Theageof
onsetismainlybetween12and23yearsold,accountingfor94.64% ofthetotalcase.Themainaffectedpopulationwasstudents,
accountingfor97.40% ofthetotalcases.92.64% ofcaseshadnohistoryofimmunizationwithvaccinescontainingrubella
components(RCV)orunknownimmunizationhistory.ThegenotypesofrubellavirusstrainsinDingxiwere1Eand2Bgenotypes.
CONCLUSIONTherubellaepidemicinDingxishowsobviousageclusteringandimmunegaps,anditisnecessarytostrengthen
vaccinationamongyoungpeopleandschoolepidemicpreventionandcontrol..
keywords: Keywords:rubella epidemiology rubellavirus genotype
文章编号:3202410011 中图分类号:R511.2 文献标志码:
基金项目:
| 作者 | 单位 |
| 田菊梅,张艳梅,陈军莲,贺晓玲 |
| Author Name | Affiliation |
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