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中国初级卫生保健:2018,32(1):92-93
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血清胱抑素C和尿微量白蛋白/肌酐比值在原发性高血压肾损害早期诊断的临床意义*
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中文摘要: 目的 探讨检测血清胱抑素C(CysC)和尿微量白蛋白/肌酐比值(mAlb/Cr,ACR)对诊断高血压早期肾损害的临床价值。方法 选取原发性高血压血肌酐(Cr)正常患者290例,检测血清CysC及尿ACR,将CysC、尿ACR与CysC与尿ACR组合比较检测阳性率。结果 血清CysC对高血压早期肾损害诊断高于尿ACR,血清CysC联合尿ACR组合诊断高血压早期肾损害显著高于单一检测。结论 血清CysC对诊断高血压早期轻度肾损害具有较高诊断价值,联合尿ACR能进一步提高对高血压早期肾功能损害的诊断。
Abstract:OBJECTIVE To investigate the clinical value of serum cystatin C (CysC) and urinary Albumin/Creatinine ratio(ACR) in the diagnosis of early renal function injury in patients with essential hypertension.METHODS SerumCysC and ACR were detected in 290 cases of essential hypertension with normal serum creatinine (Cr). RESULTS The positive rate of combined Serum CysC and ACR was obviously higher than that of either alone. CONCLUSION SerumCys C are more sensitive indexes of early renal function injury in patients with hypertension than urinary ACR. The combined determination of serum CysC and urinary ACR can improve the detection rate of early renal ftmction injury.
文章编号:3201801037     中图分类号:R544.1+4    文献标志码:
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