Abstract:Objective To investigate the effect of preoperative sugar load on blood glucose and Homa index in patients with stress hyperglycemia during perioperative period. Methods The surgical patients were divided into study Group and control group. The sugar load was given in the Study group before Operation 3h, and the control group was given routine fasting 8~12h. The blood glucose and Homa index of two groups were measured 1 days before and after operation, 3 days after operation. Results The blood glucose value and insulin were higher than the preoperative blood glucose value in the two groups of （1） and the blood glucose value and insulin were lower in the postoperative study group than in the control group (both p＞0.05). In the. (2)Study Group, the Homa-is was higher than that of the control group (p＜0.05) after Operation 1 d and postoperative 3 d. Compared with before operation, the Homa-isi of 1d and 3 d were increased (both p＜0.05) after operation in both groups, and the homa-is of 1 d and postoperative 3 d were higher in the study group than in the control group (both p＜0.05). Compared with preoperative, the homa-ir of 1d and 3d decreased (both P＜0.05) after operation in both groups, and the homa-ir of 1d after operation in the study group was lower than that of the control group (P＜0.05). Conclusion preoperative sugar load can reduce the incidence of stress hyperglycemia during perioperative period.