Abstract:OBJECTIVE To explore the effect of cross-theoretical innovative health education model on rehabilitation training of patients with chronic obstructive pulmonary disease (COPD), and provide references for rehabilitation training of COPD patients. METHODS A total of 120 patients with COPD who were treated in target hospital from January 2018 to January 2019 were enrolled. According to the random number table method, patients were randomly divided into control group and observation group, 60 cases in each group. The control group used routine health education and the observation group used cross-theory innovation health education. After 6 months, the rehabilitation training compliance, lung function (including vital capacity (VC), forced expiratory volume in 1 second (FEV1), and forced expiratory capacity in 1 second forced labor capacity ratio (FEV1/FVC)) and quality of life score were compared and analyzed.. RESULTS In the observation group, the rehabilitation training (78.33%) was significantly higher than the control group (26.67%), and there were no patients who did not undergo rehabilitation training in the observation group, and the difference were statistically significant (P<0.05); the levels of FEV1, VC and FEV1/FVC in the observation group were significantly higher than those in the control group, and the difference were statistically significant (P<0.05); the disease effect, respiratory symptoms and activity limitation scores in the observation group were significantly lower than the control group, and the difference were statistically significant (P<0.05). CONCLUSION The cross-theory innovation health education model could promote the rehabilitation training of patients with COPD on time, significantly improve the lung function of patients, and improve the quality of life of patients, which was worthy of popularization and application.