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中国初级卫生保健:2020,34(2):87-73
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格列美脲与瑞格列奈对老年2型糖尿病患者有效性和安全性的效果观察
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中文摘要: 目的 探讨格列美脲与瑞格列奈对老年2型糖尿病患者有效性和安全性的临床疗效。方法 选取2017年12月—2018年12月上海市浦东新区六灶社区卫生服务中心门诊随访的2型糖尿病患者170例,随机分为对照组(n=85)和观察组(n=85),对照组给予格列美脲,观察组给予瑞格列奈,每周根据患者血糖情况调整用药剂量,两组患者连续治疗12周后,比较临床疗效。结果 对照组与观察组的优良率分别为81.18%、82.35%,两组比较差异无统计学意义(P>0.05);经治疗后,对照组和观察组FPG、P2hBG及HbAlc水平显著下降(P<0.05),但上述指标两组比较差异无统计学意义(P>0.05);两组低血糖发生率比较差异无统计学意义(2.35%VS4.71%,P>0.05);两组患者治疗前后体质质量指数、血脂水平指标(TC、TG、HDL-C和LDL-C)、尿肌酐水平(Cr)及血压水平(收缩压和舒张压)比较差异无统计学意义(P>0.05));两组不良反应发生率比较差异无统计学意义(7.06%VS4.71%,P>0.05)。结论 格列美脲与瑞格列奈均可治疗老年2型糖尿病,延缓2型糖尿病的进程,疗效确切安全。
中文关键词: 2型糖尿病  格列美脲  瑞格列奈
Abstract:With the improvement of the national basic public health service standards and the maturation of maternal health management services, pregnant women’s schools played an extremely important role in increasing their knowledge of maternal health care. Community hospitals mainly provided basic medical care and basic public services, while maternal demand for health care services tended to be diversified, professional, and security changes, so difficultly to meet their health care service needs. Based on the convenient and effective characteristics of community Chinese medicine service, it explored the education model of integrating pregnant women’s schools into traditional Chinese medicine health care services in community hospitals, which not only promoted the development of traditional Chinese medicine services, but also improved the participation rate of pregnant women’s schools in community hospitals.
文章编号:3202001025     中图分类号:R587.1    文献标志码:
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