Abstract:OBJECTIVE To study the effect of Jianpi Liqi recipe on the tic score of children with polytractile tourette syndrome （TS）， to evaluate its clinical efficacy. METHODS 74 children with TSwere selected and randomly divided into the observation group and the control group according to the order of admission from Januany，2014 to December，2015. In the observation group， 37 cases were treated with Jianpi Liqi recipe；In the control group，37 cases were treated with routine western medicine. 4 weeks per course of treatment， continuous treatment for 6 cycles by Yale Global Tic Severity volume table（YGTSS） to evaluate two groups tic integral change compared the therapeutic effect. RESULTS There was no statistical significant difference between the two groups before YGTSS treatment（P＞0.05）. After 3 months，6 months，the treatment was significantly lower，statistical significant difference（P＜0.05）. The effective rate（83.78%）in the observation group was higher than that in the control group （62.16%）， and the adverse reaction rate（5.41%）was lower than the control group（24.32%），the differences were statistical significant Zclinical efficacy=3.019， Zclinical efficacy=4.376，（P＜0.05）. CONCLUSION The traditional Chinese medicine Jianpi Liqi could significantly reduce the TS twitch integral in children，and improve tic symptoms and high security. The clinical effect was better than the conventional western medicine，it had good clinical application value.