Abstract:Abstract: OBJECTIVE To understand the prevalence of high-risk population of cardiovascular disease (CVD) and related influ⁃ encing factors in Changshu, and to provide theoretical basis for scientific prevention and control measures of cardiovascular disease in Changshu. METHODS From November 2018 to July 2019, a total of 11 809 urban and rural residents from 6 towns in Changshu were selected by cluster random sampling method for face-to-face questionnaire survey, physical examination and biochemical index detection. RESULTS A total of 1 854 high risk subjects were detected, and the high risk rate was 15.70%. The high risk rate of fe⁃ males (16.60%) was higher than that of males (14.40%) (χ 2 =9.828, P<0.01). Older age, widowed, smoking and central obesity were the risk factors for CVD high-risk population in Changshu male residents (OR=2.818, 1.529, 1.341, 1.468). Administrative/profes⁃ sional and technical personnel, tea drinking, normal day shift OR variable working hours were protective factors (OR=0.378, 0.706, 0.426, 0.449). Older age, widowed and central obesity were the risk factors for CVD high-risk population in female residents (OR= 4.253, 1.423, 1.428). Body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), serum uric acid (UA), fasting plasma glucose (FPG), total cholesterol (TC) and triglyceride (TG) in male and female CVD high-risk group were higher than those in non-high-risk group, there was statistically significant difference (P<0.01). CONCLUSION It should actively carry out comprehensive prevention measures, do a good job of regular screening of high-risk groups, control the risk of cardiovascular dis⁃ ease, encourage residents to limit smoking, moderate tea drinking, reasonable diet, body weight control, strengthen exercise, and pro⁃ mote the formation of healthy lifestyle.