本文已被：浏览 5438次 下载 0次
中文摘要: 摘 要：目的：分析2021—2024年南通市经济技术开发区(以下简称南通市开发区)城市癌症早诊早治项目风险评估 及临床筛查结果，对项目风险评估效果进行评价。方法：收集整理2021—2024年南通市开发区城市癌症早诊早治项目评估 和临床筛查资料，对比该区肿瘤登记报告库信息。结果：2021—2024年南通市开发区城市癌症早诊早治项目共调查评估7 232人，其中，癌症高风险2819人，高风险率为38.98%;参与评估居民男女性别比为1:1.51,平均年龄(61.4±7.9)岁； 各癌种高风险率依次为乳腺癌(23.6%)、肺癌(22.4%)、胃癌(13.3%)、结直肠癌(12.5%)、肝癌(4.9%);男性肺癌、胃 癌、结直肠癌、肝癌高风险率均高于女性，差异有统计学意义 (P<0.01), 多癌种高风险率呈随年龄变化的趋势(x² 值分 别为19.236、10.186、145.755、47.287,P<0.01); 临床筛查率依次为乳腺癌(55.3%)、肺癌(54.1%)、肝癌(53.9%)、胃 癌(21.6%)、结直肠癌(19.9%),筛查阳性检出率分别为肺癌(1.8%)、肝癌 (O) 、 胃癌(0.5%)、结直肠癌(1.1%)、乳腺 癌(0.9%);风险评估模型特异度为肺癌(77.6%)、肝癌(95.2%)、胃癌(86.7%)、结直肠癌(85.6%)、乳腺癌(85.8%); 结直肠癌高风险人群癌症发生率高于非高风险人群，差异有统计学意义 (x²=5.192,P<0.05) 。 结论：应加大个体化健康 教育力度，提高居民健康素养水平，制定、健全癌症早诊早治策略及体系
Abstract:Abstract: OBJECTIVE To analyze the risk assessment and clinical screening results of the Urban Cancer Early Diagnosis and Treatment Project in Nantong Economic and Technological Development Zone(Nantong Development Zone)from 2021 to 2024,and to evaluate the effectiveness of the project's risk assessment.METHODS Data from the project's risk assessment and clinical screening conducted in Nantong Development Zone from 2021 to 2024 were collected and organized,and compared with information from the distriet's tumor registry database.RESULTS From 2021 to 2024,the project assessed 7,232 residents,identifying 2,819 high-risk individuals for cancer(38.98%).The male-to-female ratio among assessed residents was 1:1.51,with an average age of(61.4± 7.9)years.The cancer types with the high-risk rates were breast cancer(23.6%),lung cancer(22.4%),gastric cancer(13.3%), colorectal cancer(12.5%),and liver cancer(4.9%).The high-risk rates for lung cancer,gastric cancer,colorectal cancer,and liver cancer were significantly higher in males than females(P<0.01).High-risk rates for multiple cancer types showed an age-related trend(x²=19.236,10.186,145.755,47.287;P<0.01).The clinical screening rates were breast cancer(55.3%),lung cancer(54.1%), liver cancer(53.9%),gastric cancer(21.6%),and colorectal cancer(19.9%).The positive detection rates for screening were lung cancer(1.8%),liver cancer(0%),gastric cancer(0.5%),colorectal cancer(1.1%),and breast cancer(0.9%);the specificity of the risk assessment models for each cancer type were lung cancer(77.56%),liver cancer(95.15%),gastric cancer(86.65%), colorectal cancer(85.58%),and breast cancer(85.80%).The cancer incidence rate among high-risk individuals for colorectal cancer was higher than that among non-high-risk individuals,and the difference was statistically significant(x²=5.192,P<0.05).
CONCLUSION Efforts should be intensified to enhance personalized health education,improveresidents'health literacy,and establish and refine strategies and systems for early cancer diagnosis and treatment.
文章编号：3202410007 中图分类号：R730.1 文献标志码：
基金项目:
| 作者 | 单位 |
| 姚珅，潘少聪 |
| Author Name | Affiliation |
引用文本：