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中国初级卫生保健:2024,38(5):87-90
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基于文献的痞满证候特征及用药规律研究*
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中文摘要: 摘 要:目的:收集与整理2001—2022年中国知网 (CNKI) 数据库收录有关治疗痞满的文献,并对证型、中药处方中 的用药规律进行分析,为临床治疗痞满提供新的思路与科学依据。方法:以 “痞满”为主题词在CNKI数据库中进行检索, 检索时间为2001—2022年。通过筛选共纳入符合标准的文献67篇,提取文献中的证候及药物组成,统计不同证候类型及中 草药的出现频次,选取出现频次≥5次的证候类型为高频证型,出现频次≥20次的中药为高频药物,并对高频药物进行关联 规则与聚类分析。结果:67篇文献共包含19个证型,其中高频证型有湿热蕴脾证、肝胃不和证、寒热错杂证、脾虚证、脾 虚气滞证和肝郁脾虚证。67篇文献共包含中药处方116首,处方中包含的中药种类共159种,其中使用频次最高的是茯苓 (46.55%)、陈皮(43.97%)、黄连(41.38%)、党参(40.52%)。聚类分析结果显示,23味高频药物聚为7类最佳。结论:痞 满以湿热蕴脾证为主,治疗以调理脾胃升降,行气除痞消满为基本法则,佐以清热祛湿、理气消滞、健脾益气。
Abstract:Abstract:OBJECTIVE The literatures on the treatment of ruffian were collected and sorted out in CNKI database from 2001 to 2022,and the patterns of syndrome and drug use in Traditional Chinese Medicine prescriptions were analyzed to provide new ideas and scientific basis for clinical treatment of ruffian. METHODS The search was conducted in CNKI database with “fullness”as the main title,and the search time was from 2001 to 2022. A total of 67 literatures meeting the criteria were included through screening, the syndrome and drug composition in the literatures were extracted,and the occurrence frequency of different syndrome types and Chinese herbs was counted. The syndrome types with ≥5 frequency were selected as high-frequency syndrome types,and the Chi⁃ nese medicines with ≥20 frequency were selected as high-frequency drugs. Association rules and cluster analysis were conducted for high-frequency drugs. RESULTS There were 19 syndromes in 67 literatures,among which the high frequency syndromes were syndromes of damp-heat accumulation in spleen, disharmonious liver and stomach, mixed cold and heat, spleen deficiency, spleen deficiency qi stagnation and liver stagnation and spleen deficiency. A total of 116 Chinese medicine prescriptions were includ⁃ ed in 67 literatures,and 159 kinds of Chinese medicine were included in the prescriptions,among which the most frequently used were poria cocos (46.55%),dried orange peel (43.97%),coptis (41.38%) and codonopsis (40.52%). The results of cluster analysis showed that 7 kinds of 23 flavors of high frequency drugs were the best. CONCLUSION The main treatment of ruffian is to regulate the rise and fall of the spleen and stomach,and the basic principles of qi removal and stagnation are supplemented by clearing heat and dampness,regulating qi and eliminating stagnation,and strengthening the spleen and invigorating qi.
文章编号:3202410022     中图分类号:R256.32    文献标志码:
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