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中国初级卫生保健:2024,38(12):110-112
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运动康复结合药物治疗对心绞痛患者 血脂、血管内皮功能及生活质量的影响 *
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中文摘要: 摘 要:目的:探讨运动康复结合药物治疗对心绞痛患者血脂、血管内皮功能及躯体运动功能的影响。方法:选择 2021—2022 年上海市浦东新区孙桥社区卫生服务中心收治的稳定型心绞痛患者 134 例,将其随机分为对照组 (n=67) 和观 察组 (n=67)。给予对照组患者酒石酸美托洛尔片联合通心络胶囊治疗,观察组在此基础上结合运动康复治疗,治疗 8 周后 比较两组患者临床疗效。结果:治疗后,观察组患者三酰甘油、总胆固醇、高密度脂蛋白胆固醇及低密度脂蛋白胆固醇等血 脂指标改善幅度均优于对照组,差异均有统计学意义 (t 值分别为 4.115、11.806、2.898、2.699,P<0.05);观察组患者血清 内皮素-1 和一氧化碳等血管内皮功能指标改善幅度均高于对照组,差异均有统计学意义 (t 值分别为 7.570、4.927,P< 0.05);观察组患者西雅图心绞痛量表中躯体活动受限程度、心绞痛稳定状态、心绞痛发作情况、治疗满意程度、基本认知 程度 5 个项目评分提高幅度均高于对照组,差异均有统计学意义 (t 值分别为 13.314、15.477、18.946、16.024、15.128,P< 0.05)。结论:运动康复结合药物治疗心绞痛有助于提高治疗效果,可调节患者血管内皮功能,改善患者血脂水平,提高患 者生活质量,从而有效抑制心绞痛发作。
Abstract:Abstract: OBJECTIVE To explore the influence of exercise rehabilitation combined with Tongxinluo capsule on blood lipids, vascular endothelial function and physical motor function of stenocardia. METHODS 134 cases of stenocardia admitted to Sunqiao Community Health Service Center in Pudong New Area from Shanghai from 2021 to 2022 were randomly divided into two groups, a control group (n=67) and an observation group (n=67). The control group patients were given Tongxinluo capsule, and the patients of observation group were given exercise rehabilitation on the basis of control group. After 8 weeks, the clinical efficacy of two groups were analyzed. RESULTS Compared with control group, the blood fat levels of observation group were significantly improved after treatment (t=4.115, 11.806, 2.898, 2.699, P<0.05). The exercise rehabilitation combined with Tongxinluo capsule could significantly improve the vessel endothelial function of two groups, there was no significant difference (t=7.570, 4.927, P<0.05). Compared with control group, the scores of seattle angina questionnaire scale had been a significant increase of observation group (t=13.314, 15.477, 18.946, 16.024, 15.128, P<0.05). CONCLUSION The exercise rehabilitation combined with Tongxinluo capsule can regulate vascular endothelial function, improve blood lipid level and physical movement function, and inhibit angina attacks of stenocardia.
文章编号:3202410029     中图分类号:R541    文献标志码:
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李东,樊爱青  
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